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3βHSD1-IN-1

3βHSD1-IN-1 (Compound 46) is a 3β-hydroxysteroid dehydrogenase 1 (3βHSD1) inhibitor with an IC50 of 55 nM. 3βHSD1-IN-1 can effectively inhibit androgen receptor activity. 3βHSD1-IN-1 can be used in the research of diseases such as prostate cancer[1].

Product Specifications

CAS Number

[3082852-63-6]

UNSPSC

12352100

Target

3β-HSD; Androgen Receptor

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

CC1=C(C(O)=C(C=C1C2=NC3=C(C(C(C)(CC3)C)=O)S2)F)F

Molecular Formula

C16H15F2NO2S

Molecular Weight

323.36

References & Citations

[1]Shaun R. Stauffer, et al. 3βHSD1 INHIBITORS AND COMPOSITIONS AND USES THEREOF. WO2025085527A1. 2025-04-24.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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