3βHSD1-IN-1
3βHSD1-IN-1 (Compound 46) is a 3β-hydroxysteroid dehydrogenase 1 (3βHSD1) inhibitor with an IC50 of 55 nM. 3βHSD1-IN-1 can effectively inhibit androgen receptor activity. 3βHSD1-IN-1 can be used in the research of diseases such as prostate cancer[1].
Product Specifications
CAS Number
[3082852-63-6]
UNSPSC
12352100
Target
3β-HSD; Androgen Receptor
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CC1=C(C(O)=C(C=C1C2=NC3=C(C(C(C)(CC3)C)=O)S2)F)F
Molecular Formula
C16H15F2NO2S
Molecular Weight
323.36
References & Citations
[1]Shaun R. Stauffer, et al. 3βHSD1 INHIBITORS AND COMPOSITIONS AND USES THEREOF. WO2025085527A1. 2025-04-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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