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(R, R) -Abacavir

(R, R) -Abacavir is the (R, R) -enantiomer of Abacavir. Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. Abacavir shows anticancer activity in prostate cancer cell lines. Abacavir can trespass the blood-brain-barrier and suppresses telomerase activity[1].

Product Specifications

CAS Number

1443421-67-7

UNSPSC

12352005

Target

Apoptosis; Drug Isomer; HIV; Reverse Transcriptase; Telomerase

Related Pathways

Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Smiles

OC[C@@H](C=C1)C[C@H]1N2C3=NC(N)=NC(NC4CC4)=C3N=C2

Molecular Formula

C14H18N6O

Molecular Weight

286.33

References & Citations

[1]Vukkum P, et al. Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, its Related Substances, and Degradation Products. Sci Pharm. 2012 Oct-Dec;80 (4) :903-21.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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