(R, R) -Abacavir
(R, R) -Abacavir is the (R, R) -enantiomer of Abacavir (HY-17423) . Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. Abacavir shows anticancer activity in prostate cancer cell lines. Abacavir can trespass the blood-brain-barrier and suppresses telomerase activity[1].
Product Specifications
CAS Number
[1443421-67-7]
UNSPSC
12352005
Target
Apoptosis; Drug Isomer; HIV; Reverse Transcriptase; Telomerase
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Others
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Smiles
OC[C@@H](C=C1)C[C@H]1N2C3=NC(N)=NC(NC4CC4)=C3N=C2
Molecular Formula
C14H18N6O
Molecular Weight
286.33
References & Citations
[1]Vukkum P, et al. Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, its Related Substances, and Degradation Products. Sci Pharm. 2012 Oct-Dec;80 (4) :903-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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