GSPT1 degrader-7
GSPT1 degrader-7 (Example 43) is a molecular glue degrader targeting GSPT1. GSPT1 degrader-7 has an EC50 of 0.2 nM in DF15 multiple myeloma cells. GSPT1 degrader-7 can be used in the study of cancer[1].
Product Specifications
CAS Number
[3082942-43-3]
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(C=C1F)OCC2=CC=CC=C2)NCC3=CC=C4C(N(CC4=C3F)C5CCC(NC5=O)=O)=O
Molecular Formula
C28H24F2N4O5
Molecular Weight
534.51
References & Citations
[1]Mimi L, et al. Gspt1 compounds and methods of use of the compounds. WO2025085416A1. 2025-04-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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