PBRM1/SMARCA2,4 binder-1
PBRM1/SMARCA2,4 binder-1 (Compound 17) is a binder of PBRM1, SMARCA2, and SMARCA4 (IC50: 0.083, 0.153, and 0.046 μM, respectively) [1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC1=C2C(NC(N=C(CC3=CC=CC=C3)N4)=C2C4=O)=CC=C1
Molecular Formula
C17H13N3O2
Molecular Weight
291.30
References & Citations
[1]Boerth J A, et al. Discovery of Pyrimidoindolones as Novel Family VIII Bromodomain Binders[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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