Amb929
Amb929 (ZINC000002782982), a nsp3 ligand, is an anti-SARS-CoV-2 agent. Amb929 inhibits SARS-CoV2-mNG replication in VeroE6 cells with an EC50 of 34.7 µM. Amb929 has limited and moderate cytotoxicity for VeroE6 cells (CC50: 281 µM) . Amb929 also inhibits SARS-CoV-2-mNG replication in Human Airway Epithelium (HAE) [1].
Product Specifications
CAS Number
438196-25-9
Product Name Alternative
ZINC000002782982
UNSPSC
12352100
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC(C)COC1=CC(C2=NC3=CC=CC=C3C(C(NC(NC4=CC=C(C(OC)=O)C=C4)=S)=O)=C2)=CC=C1
Molecular Formula
C29H27N3O4S
Molecular Weight
513.61
References & Citations
[1]Mathilde Galais, et al. Highly potent antiviral drug candidates targeting SARS-CoV-2 nsp3 and nsp5. bioRxiv 2025.04.28.650947.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
