Boc-Dipiperidine-KLHDC2 ligand 1
Boc-Dipiperidine-KLHDC2 ligand 1 is an E3 ligase ligand-linker conjugate that incorporates a KLHDC2 ligand. Boc-Dipiperidine-KLHDC2 ligand 1 can be used for synthesis of PROTAC BRD4 Degrader-31 (HY-174210).
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(OC)C1=C2C(C(C3CCC4C3)C4C(C5=CC(OCCC6CCN(CC7CCN(C(OC(C)C)=O)CC7)CC6)=CC=C5)N2)=CC(Cl)=C1
Molecular Formula
C39H52ClN3O5
Molecular Weight
678.30
References & Citations
[1]Zhou H, et al. Targeted Protein Degradation by KLHDC2 Ligands Identified by High Throughput Screening. bioRxiv [Preprint]. 2025 Apr 1:2025.03.31.646306.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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