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KLHDC2 ligand 1

KLHDC2 ligand 1 is an E3 ligase ligand. KLHDC2 ligand 1 can be used for synthesis of PROTAC BRD4 Degrader-31 (HY-174210) [1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(OC)C1=C2C(C(C3CCC4C3)C4C(C5=CC(O)=CC=C5)N2)=CC(Cl)=C1

Molecular Formula

C22H22ClNO3

Molecular Weight

383.87

References & Citations

[1]Zhou H, et al. Targeted Protein Degradation by KLHDC2 Ligands Identified by High Throughput Screening. bioRxiv [Preprint]. 2025 Apr 1:2025.03.31.646306.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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