COX-2-IN-54
COX-2-IN-54 (Compound 7y) is an orally active COX-2 inhibitor with an IC50 of 4.15 μM. COX-2-IN-54 has a strong protective effect against DSS-induced ulcerative colitis and can significantly reduce tissue damage. COX-2-IN-54 has anti-inflammatory activity[1].
Product Specifications
UNSPSC
12352005
Target
COX
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C1N(C2=CC=C(CC(O)=O)C=C2)C(NC(CCCl)=O)C3=CC=CC=C31
Molecular Formula
C19H17ClN2O4
Molecular Weight
372.80
References & Citations
[1]Lai H, Liang Y, Xu J, Guo L, Deng C, Wang X, Zha D. Converting indoprofen to moderate selective COX-2 inhibitors: Design, synthesis and biological evaluation. Bioorg Chem. 2025 Jul 15;162:108593.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
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