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Sigma-2 Receptor ligand 1

Sigma-2 Receptor ligand 1 (Compound 7i) is a highly selective Sigma-2 receptor ligand with a Ki value of 40 nM. Sigma-2 Receptor ligand 1 is promising for research of Alzheimer's disease[1].

Product Specifications

UNSPSC

12352005

Target

Sigma Receptor

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

C12=CC=CC=C1C(CCN3C4C5CC(C3)C[C@@H]4C6CCOCC6)=C5N2

Molecular Formula

C22H28N2O

Molecular Weight

336.47

References & Citations

[1]Hughes AJ, et al. Discovery of Iboga-Derived Ligands for the Sigma‑2 Receptor. ACS Bio Med Chem Au. 2025 May 12;5 (3) :379-386.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Sigma 2 Receptor

Frequently Asked Questions

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