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GLUT4 activator 3

GLUT4 activator 3 (Compound 13a) is an antidiabetic agent targeting GLUT4 translocation in skeletal muscle. GLUT4 activator 3 can promote the translocation of glucose transporter 4 (GLUT4) in skeletal muscle cells. GLUT4 activator 3 reduces blood glucose in STZ-induced diabetic rats[1].

Product Specifications

CAS Number

3088771-32-5

UNSPSC

12352005

Target

GLUT

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

O=C1NN=C(C2=CC=CC=C21)CC3=CC=C(C(C(NCC4=CN(N=N4)C5=CC=CC=C5)=O)=C3)F

Molecular Formula

C25H19FN6O2

Molecular Weight

454.46

References & Citations

[1]Kushawaha AK, et al. Development of Novel Phthalazinone-Triazole Hybrids as Potential Antidiabetic Agents Targeting GLUT4 Translocation in Skeletal Muscle. J Med Chem. 2025 Jun 12;68 (11) :10722-10737.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GLUT4

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