GLUT4 activator 3
GLUT4 activator 3 (Compound 13a) is an antidiabetic agent targeting GLUT4 translocation in skeletal muscle. GLUT4 activator 3 can promote the translocation of glucose transporter 4 (GLUT4) in skeletal muscle cells. GLUT4 activator 3 reduces blood glucose in STZ-induced diabetic rats[1].
Product Specifications
CAS Number
3088771-32-5
UNSPSC
12352005
Target
GLUT
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C1NN=C(C2=CC=CC=C21)CC3=CC=C(C(C(NCC4=CN(N=N4)C5=CC=CC=C5)=O)=C3)F
Molecular Formula
C25H19FN6O2
Molecular Weight
454.46
References & Citations
[1]Kushawaha AK, et al. Development of Novel Phthalazinone-Triazole Hybrids as Potential Antidiabetic Agents Targeting GLUT4 Translocation in Skeletal Muscle. J Med Chem. 2025 Jun 12;68 (11) :10722-10737.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GLUT4
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