Butenafine (Hydrochloride) (Standard)

Rilpivirine (hydrochloride) (Standard) is the analytical standard of Rilpivirine (hydrochloride) . This product is intended for research and analytical applications. Rilpivirine (R278474) hydrochloride is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI) . Rilpivirine hydrochloride has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM) . Rilpivirine hydrochloride has a high genetic barrier to resistance development of HIV[1][2].

Product Specifications

CAS Number

[101827-46-7]

Product Name Alternative

KP363 (Hydrochloride) (Standard)

UNSPSC

12352005

Target

Antibiotic; Fungal; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

CN(CC1=CC=C(C(C)(C)C)C=C1)CC2=C3C=CC=CC3=CC=C2.[H]Cl

Molecular Formula

C23H28ClN

Molecular Weight

353.93

References & Citations

[1]Singal A. Butenafine and superficial mycoses: current status. Expert Opin Drug Metab Toxicol. 2008 Jul;4 (7) :999-1005.|[2]Kokjohn K, Bradley M, Griffiths B, Ghannoum M. Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria. Int J Dermatol. 2003 Sep;42 Suppl 1:11-7.|[3]Syed TA, Maibach HI. Butenafine hydrochloride: for the treatment of interdigital tinea pedis. Expert Opin Pharmacother. 2000 Mar;1 (3) :467-73.|[4]McNeely W, Spencer CM. Butenafine. Drugs. 1998 Mar;55 (3) :405-12; discussion 413.|[5]Butenafine