(R, S, S) -VH032-Me-N-Boc-7-aminoheptanoic acid (TFA)
(R, S, S) -VH032-Me-N-Boc-7-aminoheptanoic acid TFA is a conjugate of an E3 ubiquitin ligase ligand (HY-112078) and a linker (HY-W012001) . (R, S, S) -VH032-Me-N-Boc-7-aminoheptanoic acid TFA can be used as an intermediate in the synthesis of dTAGV-1 hydrochloride (HY-145514C) [1].
Product Specifications
UNSPSC
12352100
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C)(C)[C@H](NC(CCCCCCNC(OC(C)(C)C)=O)=O)C(N1[C@@H](C(N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C)=O)C[C@H](O)C1)=O.OC(C(F)(F)F)=O
Molecular Formula
C37H54F3N5O8S
Molecular Weight
785.91
References & Citations
[1]Nabet B, et al. Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nat Commun. 2020 Sep 18;11 (1) :4687.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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