(S, R, S) -AHPC-Me-N-Boc-7-aminoheptanoic acid
(S, R, S) -AHPC-Me-N-Boc-7-aminoheptanoic acid is a conjugate of an E3 ligase ligand and a linker, which can be used for the synthesis of PROTAC dTAGV-1 TFA (HY-145514) [1].
Product Specifications
CAS Number
[2451573-91-2]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C)(C)OC(NCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O)=O)=O
Molecular Formula
C35H53N5O6S
Molecular Weight
671.89
References & Citations
[1]Nabet B, et al. Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nat Commun. 2020 Sep 18;11 (1) :4687.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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