TE-11
TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. TE-11 ameliorates CD-like colitis, reduces MIF-induced eosinophil and neutrophil migration, and prevents M1 polarization and associated metabolic reprogramming[1].
Product Specifications
CAS Number
160488-11-9
UNSPSC
12352005
Target
Macrophage migration inhibitory factor (MIF)
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C1C2=CC=CC=C2CC/C1=C\C3=NC=CC=C3
Molecular Formula
C16H13NO
Molecular Weight
235.28
References & Citations
[1]Eszter Vámos, MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn's disease-like colitis in male mice. Front Immunol. 2025 Apr 22:16:1558079.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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