Aβ1–42 aggregation inhibitor 3
Aβ1–42 aggregation inhibitor 3 (Compound 3b) is an acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor (IC50 values are 1.634 and 0.0285 μM, respectively) . Aβ1–42 aggregation inhibitor 3 can inhibit the aggregation of Aβ1-42. Aβ1–42 aggregation inhibitor can be used in Alzheimer's disease (AD) research[1].
Product Specifications
CAS Number
[32527-84-7]
UNSPSC
12352005
Target
Amyloid-β; Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
NC1=C(SC2=CC=C([N+]([O-])=O)C=C2)C(C)=NN1C3=CC=CC=C3
Molecular Formula
C16H14N4O2S
Molecular Weight
326.37
References & Citations
[1]Rani P, et al. Design and development of sulfenylated 5-aminopyrazoles as inhibitors of acetylcholinesterase and butyrylcholinesterase: exploring the implication for Aβ1-42 aggregation inhibition in Alzheimer's disease. RSC Med Chem. 2025 Apr 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9920346-01 48 Well
Mouse Keratinocyte Differentiation-Associated Protein (KRTDAP) ELISA Kit
Ask
View Details MBS9920346-02 96 Well
Mouse Keratinocyte Differentiation-Associated Protein (KRTDAP) ELISA Kit
Ask
View Details MBS9920346-03 5x 96 Well
Mouse Keratinocyte Differentiation-Associated Protein (KRTDAP) ELISA Kit
Ask
View Details MBS9920346-04 10x 96 Well
Mouse Keratinocyte Differentiation-Associated Protein (KRTDAP) ELISA Kit
Ask
View Details 
MBS6365257-01 0.1 mL
ZFYVE1, NT (ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1, Zinc finger FYVE domain-containing protein 1, Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1) (MaxLight 650)
Ask
View Details