KTD-092
KTD-092 is a hit for DYRK1A inhibition, with an IC50 of 22 nM for human DYRK1A. KTD-092 can be used in the research for Down syndrome (DS), Alzheimer's disease (AD), autism spectrum disorder (ASD), diabetes and other neurodegenerative diseases[1].
Product Specifications
UNSPSC
12352005
Target
DYRK
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Smiles
CCN1C=NN=C1C2=NC(NC(C3=CC(OC)=C(C=C3OC)OC)=O)=CC=C2
Molecular Formula
C19H21N5O4
Molecular Weight
383.40
References & Citations
[1]Sujeong Hong, et al. Discovery of 2- (1,2,4-triazol-3-yl) pyridine KTD-092 as a novel DYRK1A. Wiley Online Library inhibitor. 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DYRK1
Curated Selection
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