VEGFR-2-IN-68
VEGFR-2-IN-68 (13b) is a VEGFR-2 inhibitor, with an IC50 of 41.51 nM. VEGFR-2-IN-68 (13b) induces apoptosis and G2/M phase arrest. VEGFR-2-IN-68 (13b) exhibits anti-metastatic properties in cancer cells[1].
Product Specifications
UNSPSC
12352005
Target
Ferroptosis
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C1=NN(/C(S1)=N/N=C(C2=CC(NC(C3=CC=C(C=C3)C)=O)=CC=C2)\C)C4=CC=C(C=C4)C)=O
Molecular Formula
C27H25N5O2S
Molecular Weight
483.58
References & Citations
[1]Xinxin Song, et al. Cytosolic cytochrome c represses ferroptosis. Cell Metab. 2025 Apr 8:S1550-4131 (25) 00149-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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