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VEGFR-2-IN-68

VEGFR-2-IN-68 (13b) is a VEGFR-2 inhibitor, with an IC50 of 41.51 nM. VEGFR-2-IN-68 (13b) induces apoptosis and G2/M phase arrest. VEGFR-2-IN-68 (13b) exhibits anti-metastatic properties in cancer cells[1].

Product Specifications

UNSPSC

12352005

Target

Ferroptosis

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC(C1=NN(/C(S1)=N/N=C(C2=CC(NC(C3=CC=C(C=C3)C)=O)=CC=C2)\C)C4=CC=C(C=C4)C)=O

Molecular Formula

C27H25N5O2S

Molecular Weight

483.58

References & Citations

[1]Xinxin Song, et al. Cytosolic cytochrome c represses ferroptosis. Cell Metab. 2025 Apr 8:S1550-4131 (25) 00149-4.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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