T3SS-1-IN-1

T3SS-1-IN-1 (Compound C26) is a T3SS-1 inhibitor. T3SS-1-IN-1 inhibits the secretion of SipA and the activity of HilD (IC50 values are 29.2 and 16.9 μM, respectively) . T3SS-1-IN-1 can be used for the study of anti-virulence of Salmonella[1].

Product Specifications

CAS Number

[930993-54-7]

UNSPSC

12352100

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(CN(CC1=CC=C(Br)S1)C)NCC2=CC3=C(C=C2)OCO3

Molecular Formula

C16H17BrN2O3S

Molecular Weight

397.29

References & Citations

[1]Boudrioua A, et al. Discovery of synthetic small molecules targeting the central regulator of Salmonella pathogenicity. Sci Adv. 2025 Apr 11;11 (15) :eadr5235.