TarO-IN-1

TarO-IN-1 (Compound 18a) is a TarO inhibitor and has antibacterial activity. TarO-IN-1 has β-lactam sensitizing and anti-biofilm activities against MRSA. TarO-IN-1 can be used for research of β-lactam resistance[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[C@H](N(C(CCN1C(N=CC=C2)=C2C(C=C1)=O)=O)C(O3)=O)[C@H]3C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4

Molecular Formula

C23H17F6N3O4

Molecular Weight

513.39

References & Citations

[1]Zhong Y, et al. Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus. NPJ Antimicrob Resist. 2025 Apr 12;3 (1) :28.