Adenosine-3',5'-bisphosphate (ammonium)
Adenosine-3',5'-bisphosphate (ammonium) is a XRN1 inhibitor (IC50 = 36 nM) . Adenosine-3',5'-bisphosphate (ammonium) can be used in the study of colorectal cancer, breast cancer and lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
Small Interfering RNA (siRNA)
Related Pathways
Epigenetics
Field of Research
Cancer
Concentration
100 mM * 1 mL in Water
Purity
99.16
Smiles
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2.N.N.N
Molecular Formula
C10H24N8O10P2
Molecular Weight
478.29
References & Citations
[1]Lockbaum GJ, et al. Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor. Commun Biol. 2025 Apr 9;8 (1) :589.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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