Arachidonic acid leelamide

Arachidonic acid leelamide, a Leelamine (HY-W005629) analog, is a pyruvate dehydrogenase kinase (PDK) inhibitor. Arachidonic acid leelamide can be used for the study of breast cancer[1][2].

Product Specifications

CAS Number

[2841710-23-2]

UNSPSC

12352005

Target

PDHK

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

C[C@@]12C3=CC=C(C(C)C)C=C3CC[C@@]1([H])[C@@](C)(CCC2)CNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O

Molecular Formula

C40H61NO

Molecular Weight

571.92

References & Citations

[1]Fiocchetti M, et al Dissecting the 17β-estradiol pathways necessary for neuroglobin anti-apoptotic activity in breast cancer. J Cell Physiol. 2018 Jul;233 (7) :5087-5103. |[2]Aicher TD, et al. Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK) . Bioorg Med Chem Lett. 1999 Aug 2;9 (15) :2223-8.