SARS-CoV-2 3CLpro-IN-31
SARS-CoV-2 3CLpro-IN-31 (Compound 13c) is a potent SARS-CoV-2 3CL protease (3CLpro) inhibitor of with an IC50 value of 37.33 nM. SARS-CoV-2 3CLpro-IN-31 blocks viral polyprotein cleavage and inhibits SARS-CoV-2 replication. SARS-CoV-2 3CLpro-IN-31 is promising for research of SARS-CoV-2 infection[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CS(=O)(N[C@H](C(N(C)[C@H](C(N1[C@H](C#N)C[C@]2(C(NC3=C2C=CC=C3)=O)C1)=O)CC(C)C)=O)C)=O
Molecular Formula
C23H31N5O5S
Molecular Weight
489.59
References & Citations
[1]Hu L, et al. Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors. ACS Med Chem Lett. 2025 Apr 14;16 (5) :790-796.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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