E3 Ligase Ligand-linker Conjugate 181
E3 Ligase Ligand-linker Conjugate 181 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 181 can be used to synthesize MS115 (HY-173561) [1].
Product Specifications
CAS Number
[2850354-06-0]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
CC(N=CS1)=C1C(C=C2)=CC=C2[C@@H](NC([C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NC(C4(CC4)F)=O)=O)=O)CC(NCCOCCOCCOCCOCCOCCC(O)=O)=O
Molecular Formula
C41H60FN5O12S
Molecular Weight
866.00
References & Citations
[1]Zhong Y, et al. Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader. J Med Chem. 2025 Apr 24;68 (8) :8543-8563.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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