E3 Ligase Ligand-linker Conjugate 181

E3 Ligase Ligand-linker Conjugate 181 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 181 can be used to synthesize MS115 (HY-173561) [1].

Product Specifications

CAS Number

[2850354-06-0]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

CC(N=CS1)=C1C(C=C2)=CC=C2[C@@H](NC([C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NC(C4(CC4)F)=O)=O)=O)CC(NCCOCCOCCOCCOCCOCCC(O)=O)=O

Molecular Formula

C41H60FN5O12S

Molecular Weight

866.00

References & Citations

[1]Zhong Y, et al. Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader. J Med Chem. 2025 Apr 24;68 (8) :8543-8563.