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PRMT5 ligand 2

PRMT5 ligand 2 (Compound 38) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . PRMT5 ligand 2 can be used for synthesis MS115 (HY-173561) [1].

Product Specifications

CAS Number

[1616391-79-7]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(NC[C@@H](CN1CC2=C(CC1)C=CC=C2)O)C3=NC=NC(NC4CCNCC4)=C3

Molecular Formula

C22H30N6O2

Molecular Weight

410.51

References & Citations

[1]Zhong Y, et al. Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader. J Med Chem. 2025 Apr 24;68 (8) :8543-8563.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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