D-myo-Inositol-1,2,4,5-tetraphosphate (tetrasodium salt)

D-myo-Inositol-1,2,4,5-tetraphosphate (DL-Ins- (1,2,4,5) P4) tetrasodium is raracemic regioisomer of myo-inositol tetrakisphosphates (IP4s) . D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium is an Ins (1,4,5) P3 receptor agonist with a Ki of 11 nM. D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium induces Ca2+ mobilization with an EC50 value of 0.22 μM in CHO cells[1].

Product Specifications

CAS Number

[154278-46-3]

Product Name Alternative

Ins (1,2,4,5) P4 (tetrasodium salt) ; 1,2,4,5-IP4 (tetrasodium salt)

UNSPSC

12352211

Target

Calcium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Purity

Solubility

H2O : 50 mg/mL (ultrasonic; warming)

Smiles

O[C@@H]1[C@H]([C@@H]([C@H]([C@H]([C@H]1OP(O)(O[Na])=O)OP(O)(O[Na])=O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O

Molecular Formula

C6H12Na4O18P4

Molecular Weight

588.00

References & Citations

[1]Burford NT, et al. Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. Cell Calcium. 1997 Apr;21 (4) :301-10.