SARS-CoV-2 Mpro-IN-42

SARS-CoV-2 Mpro-IN-42 (compound C5) is a potent SARS-CoV-2 Mpro inhibitor with an IC50 of 33.6 nM. SARS-CoV-2 Mpro-IN-42 can be used in the study of SARS-CoV-2[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

N#CC1=NN(C2=CC=C(C(F)(F)F)C(F)=C2)C(N(CC(C3=NC=CC=C3)=O)C1=O)=O

Molecular Formula

C18H9F4N5O3

Molecular Weight

419.29

References & Citations

[1]Yang Z, et al. A deep learning model for structure-based bioactivity optimization and its application in the bioactivity optimization of a SARS-CoV-2 main protease inhibitor. Eur J Med Chem. 2025 Jul 5;291:117602.