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IRE1-IN-2

IRE1-IN-2 (compound G15) is a potent IRE1 inhibitor. IRE1-IN-2 inhibits FFA-induced lipid accumulation with an IC50 of 2.06 μM[1].

Product Specifications

UNSPSC

12352005

Target

IRE1

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Metabolic Disease; Inflammation/Immunology

Smiles

O=C(OC)C1=CO[C@H]([C@]2([C@@]1(CC=C2COC(C=C)=O)[H])[H])OCC

Molecular Formula

C16H20O6

Molecular Weight

308.33

References & Citations

[1]Feng ZT, et al. Development of new genipin derivatives as potential NASH treatments: Design, synthesis and action mechanism. Bioorg Chem. 2025 Jun 1;159:108403.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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