FAK-IN-25

FAK-IN-25 (4c) is a FAK inhibitor with an IC50 of 50.98 nM. FAK-IN-25 (4c) induces apoptosis and causes cell cycle arrest at G1 phase. FAK-IN-25 (4c) can be used in cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; FAK

Related Pathways

Apoptosis; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(C1=C(N)C2=C(C3=CC=CS3)C=C(C4=NC=CN=C4)N=C2S1)C5=CC=C(Cl)C=C5

Molecular Formula

C22H13ClN4OS2

Molecular Weight

448.95

References & Citations

[1]Azza Ismail, et al. Exploring Thieno/Furo[2,3-b]pyridines as new scaffolds for potential FAK inhibition: Design, synthesis, biological evaluation and in silico studies. Bioorg Chem. 2025 Jun 1:159:108392.