COX-2-IN-53

COX-2-IN-53 (compound 9) is a potent COX-2 inhibitor with an IC50 of 0.373 μM. COX-2-IN-53 reduces radiation-induced oxidative stress[1].

Product Specifications

UNSPSC

12352005

Target

COX

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

O=C(CSCC(NC1=CC=C(S(=O)(N)=O)C=C1)=O)NN2CCOCC2

Molecular Formula

C14H20N4O5S2

Molecular Weight

388.46

References & Citations

[1]Ghorab MM, et al. New acetamide-sulfonamide scaffolds with potential renal radiomodulatory effects: Insights into NF-κB pathway interactions. Bioorg Chem. 2025 Jun 15;160:108439.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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