OSUAB-0284
OSUAB-0284 is a bacterial topoisomerase inhibitor. OSUAB-0284 has significant anti-staphylococcal activity, especially against methicillin-resistant Staphylococcus aureus (MRSA) . OSUAB-0284 exerts its antibacterial effect by inhibiting bacterial topoisomerase. OSUAB-0284 can be used to study infections caused by drug-resistant bacteria such as MRSA[1].
Product Specifications
CAS Number
[3053515-60-6]
UNSPSC
12352005
Target
Antibiotic; Bacterial; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O[C@@H](CC1=C(F)C=NC2=CC=C(OC)N=C12)[C@H](OC3)OC[C@@H]3NCC4=CN=C(OC5)C(NC5=O)=N4
Molecular Formula
C22H23FN6O6
Molecular Weight
486.45
References & Citations
[1]West JS, et al. Decagram-Scale Synthesis of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284. Org Process Res Dev. 2025 Mar 26;29 (4) :1136-1151.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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