TcO-ABX474
TcO-ABX474 (TcO-5) is a potent prostate-specific membrane antigen (PSMA) inhibitor with a Kd value of 6.1 nM. TcO-ABX474 inhibits prostate cancer cell growth and metastasis. TcO-ABX474 is promising for research of prostate cancer[1].
Product Specifications
CAS Number
3019987-06-2
Product Name Alternative
TcO-5
UNSPSC
12352211
Target
PSMA
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(CC[C@H](C(O)=O)NC(N[C@@H](C(O)=O)CCCCNC(CCCCCCC(NCCCC[C@H](NC([C@H](NC([C@@H](NC(CCCC[N]1(CC(C)(C)S2)CCN(CC(C)(C)S3)[Tc]132=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)C(O)=O)=O)=O)=O)O
Molecular Formula
C51H86N9O19S2Tc
Molecular Weight
1292.31
References & Citations
[1]Lis C, et al. Development of [99mTc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer. J Med Chem. 2025 Apr 10;68 (7) :7213-7231.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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