PROTAC MTP3 degrader-1
PROTAC MTP3 degrade-1 is a PROTAC based MYC degrader (Red: MYC inhibitor (HY-173469), black: linker (HY-W008296), Blue: E3 ligase ligand (HY-14658) ) [1].
Product Specifications
UNSPSC
12352005
Target
C-Myc; PROTACs
Related Pathways
Apoptosis; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
N#CC(C=C1)=CC=C1C2=CC(C3=CC=C(C(NCCCCCCNC(COC4=C(C(N(C5C(NC(CC5)=O)=O)C6=O)=O)C6=CC=C4)=O)=O)C=C3)=CC(C7=CC=CO7)=N2
Molecular Formula
C44H38N6O8
Molecular Weight
778.81
References & Citations
[1]Boyd SR, et al. MYC-Targeting PROTACs Lead to Bimodal Degradation and N-Terminal Truncation. ACS Chem Biol. 2025 Apr 18;20 (4) :896-906.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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