RAS-IN-3
RAS-IN-3 (compound 22) is a potent Ras inhibitor. ROCK-IN-12 can be used in the study of Non-small cell lung cancer and colorectal cancer [1].
Product Specifications
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Smiles
OC1=CC=C(C(S/C2=N\S3(=O)=O)=C1N2CCCCCN(C(C4=CC3=CC=C4O)=O)C5CCN(CC5)CCC)Cl.Cl
Molecular Formula
C27H34Cl2N4O5S2
Molecular Weight
629.62
References & Citations
[1]Parry CW, et al. Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras. J Med Chem. 2025 May 8;68 (9) :9129-9161.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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