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RAS-IN-3

RAS-IN-3 (compound 22) is a potent Ras inhibitor. ROCK-IN-12 can be used in the study of Non-small cell lung cancer and colorectal cancer [1].

Product Specifications

UNSPSC

12352005

Target

Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Smiles

OC1=CC=C(C(S/C2=N\S3(=O)=O)=C1N2CCCCCN(C(C4=CC3=CC=C4O)=O)C5CCN(CC5)CCC)Cl.Cl

Molecular Formula

C27H34Cl2N4O5S2

Molecular Weight

629.62

References & Citations

[1]Parry CW, et al. Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras. J Med Chem. 2025 May 8;68 (9) :9129-9161.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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