NBTIs-IN-7
NBTIs-IN-7 (compound 276) is a novel bacterial topoisomerase (NBTIs) inhibitor. NBTIs-IN-7 induces both single- and double-strand DNA strand breaks in the presence of gyrase[1].
Product Specifications
UNSPSC
12352005
Target
Topoisomerase
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C1NC2=CC(C3=CN(C4CCN(CCC5=C(F)C=NC6=CC=C(OC)N=C56)CC4)N=N3)=CC=C2OC1
Molecular Formula
C26H26FN7O3
Molecular Weight
503.53
References & Citations
[1]Toth PD, et al. Structural and Mechanistic Insights into Atypical Bacterial Topoisomerase Inhibitors. ACS Med Chem Lett. 2025 Apr 1;16 (4) :660-667.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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