TRPM2-IN-1
TRPM2-IN-1 (compound D10) is a potent TRPM2 inhibitor. TRPM2-IN-1 exhibits antistroke activity and significant neuroprotective effect. TRPM2-IN-1 can be used in the study of ischemic stroke[1].
Product Specifications
CAS Number
[2833727-43-6]
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(C1=CC(C(N(CC)CC)=O)=CC2=CC=CN21)C3=CC=CC=C3
Molecular Formula
C20H20N2O2
Molecular Weight
320.39
References & Citations
[1]Lu T, et al. Indolizine Derivatives Inhibit TRPM2 and Protect against Ischemic Brain Injury with an Extended Treatment Window. J Med Chem. 2025 Apr 10;68 (7) :7642-7661.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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