8-BuS-AMP
8-BuS-AMP is a CD39 and CD73 dual inhibitor. 8-BuS-AMP inhibits human CD39, mouse CD39 and human CD73 with Kis of 0.292, 2.19 and 1.19 μM, respectively[1].
Product Specifications
CAS Number
344402-39-7
UNSPSC
12352005
Target
NTPDase
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Purity
99.90
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2SCCCC)O[C@@H]1COP(O)(O)=O
Molecular Formula
C14H22N5O7PS
Molecular Weight
435.39
References & Citations
[1]Bi C, et al. Synthesis, Characterization, Interactions, and Immunomodulatory Function of Ectonucleotidase CD39/CD73 Inhibitor 8-Butylthioadenosine 5'-Monophosphate. ACS Pharmacol Transl Sci. 2025 Apr 3;8 (5) :1401-1415.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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