PARP1-IN-38
PARP1-IN-38 (compound ent-6_P) is a potent PARP1 inhibitor with an IC50 of 10 μM. PARP1-IN-38 shows selective cytotoxic activity in BRCA mutant cancer cells[1]
Product Specifications
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
FC1=CC2=C(C(C3C4NC5=C3C=CC=C5)=NNC2=O)C4=C1
Molecular Formula
C16H10FN3O
Molecular Weight
279.27
References & Citations
[1]Doruk YU, et al. Discovery of a Novel [6-6-5-5-6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold. ACS Med Chem Lett. 2025 Apr 3;16 (5) :776-783.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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