RIPK1-IN-30
RIPK1-IN-30 (compound 24) is a potent RIPK1 inhibitor with an IC50 of 2.01 μM. RIPK1-IN-30 exhibits protective effects in HT-29 cell model of TSZ-induced necroptosis with an EC50 of 6.77 μM[1].
Product Specifications
UNSPSC
12352005
Target
RIP kinase
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology
Smiles
FC1=CC=CC(CN2C(N(C3=CC=CC(C(CC4=CC(OCCO5)=C5C=C4)=O)=C3)CCC2)=O)=C1
Molecular Formula
C27H25FN2O4
Molecular Weight
460.50
References & Citations
[1]Liu B, et al. Discovery and Characterization of Novel Receptor-Interacting Protein Kinase 1 Inhibitors Using Deep Learning and Virtual Screening. ACS Chem Neurosci. 2025 Apr 16;16 (8) :1617-1630.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
MBS4382138-01 0.02 mg (With BSA & Azide at 0.2mg/mL)
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]
Ask
View Details MBS4382138-02 0.1 mg (With BSA & Azide at 0.2mg/mL)
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]
Ask
View Details ![Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
MBS4382138-03 0.1 mg (Without BSA & Azide at 1mg/mL)
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]
Ask
View Details MBS4382138-04 5x 0.1 mg (With BSA & Azide at 0.2mg/mL)
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]
Ask
View Details MBS4382138-05 5x 0.1 mg (Without BSA & Azide at 1mg/mL)
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody [Clone KRT20/4879R]
Ask
View Details