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E3 ligase Ligand 60

E3 ligase Ligand 60 is a ligand for E3 ligase, used for the synthesis of JV8 (HY-173433) [1].

Product Specifications

CAS Number

[2250014-82-3]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

N[C@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O

Molecular Formula

C23H32N4O3S

Molecular Weight

444.59

References & Citations

[1]Li T, et al. Non-invasive in vivo monitoring of PROTAC-mediated protein degradation using an environment-sensitive reporter. Nat Commun. 2025 Feb 22;16 (1) :1892.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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