ZK-316

ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50s ranging from 0.99 to 75.1 nM. ZK-316 can be used in the study of HIV[1].

Product Specifications

CAS Number

[3027894-30-7]

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

N#CC1=CC(C([2H])([2H])[2H])=C(OC2=C3SC=CC3=NC(NC4CCN(CC4)CC5=CC=C(C=C5)S(=O)(N)=O)=N2)C(C([2H])([2H])[2H])=C1

Molecular Formula

C27H22D6N6O3S2

Molecular Weight

554.72

References & Citations

[1]Zhang K, et al. Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability. J Med Chem. 2025 Apr 24;68 (8) :8564-8577.