K-5a2
K-5a2 is the non-isotopic form of ZK-316. ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 value ranging from 0.99 to 75.1 nM. ZK-316 can be used in the study of HIV[1].
Product Specifications
CAS Number
1810730-10-9
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
N#CC1=CC(C)=C(OC2=C3SC=CC3=NC(NC4CCN(CC4)CC5=CC=C(C=C5)S(=O)(N)=O)=N2)C(C)=C1
Molecular Formula
C27H28N6O3S2
Molecular Weight
548.68
References & Citations
[1]Zhang K, et al. Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability. J Med Chem. 2025 Apr 24;68 (8) :8564-8577.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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