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K-5a2

K-5a2 is the non-isotopic form of ZK-316 (HY-173427S) . ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 value ranging from 0.99 to 75.1 nM. ZK-316 can be used in the study of HIV[1].

Product Specifications

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

N#CC1=CC(C)=C(OC2=C3SC=CC3=NC(NC4CCN(CC4)CC5=CC=C(C=C5)S(=O)(N)=O)=N2)C(C)=C1

Molecular Formula

C27H28N6O3S2

Molecular Weight

548.68

References & Citations

[1]Zhang K, et al. Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability. J Med Chem. 2025 Apr 24;68 (8) :8564-8577.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-173427/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[1810730-10-9]

Curated Selection

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