E3 Ligase Ligand-linker Conjugate 178
E3 Ligase Ligand-linker Conjugate 178 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 178 can be used to synthesize MS2133.
Product Specifications
CAS Number
2768514-43-6
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C3=CC=C(C4=C(C)N=CS4)C=C3)CC(NCCCCCCN)=O
Molecular Formula
C34H49FN6O5S
Molecular Weight
672.85
References & Citations
[1]Yim H, et al. Discovery of the first-in-class DOT1L PROTAC degrader. Eur J Med Chem. 2025 Jul 5;291:117595.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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