(H) S (OMe) -DFR-kbt
(H) S (OMe) -DFR-kbt (compound 9) is a potent and selective TMPRSS2 inhibitor with a Ki of 0.13 nM. (H) S (OMe) -DFR-kbt can be used in the study of SARS-CoV-2[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
COCCC(N[C@@H](CC([O-])=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=[NH2+])C(C2=NC3=C(C=CC=C3)S2)=O)=O)=O)=O
Molecular Formula
C30H37N7O7S
Molecular Weight
639.72
References & Citations
[1]Ferková S, et al. Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors. Eur J Med Chem. 2025 Mar 28;294:117579.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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