15-Keto Iloprost

15-Keto Iloprost is a C-15 oxidized derivative of Iloprost (HY-A0096) . Iloprost (ZK 36374) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis[1][2].

Product Specifications

CAS Number

[155326-57-1]

UNSPSC

12352211

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer; Endocrinology; Cardiovascular Disease

Smiles

O[C@@H]1C[C@@]2([H])[C@]([C@H]1/C=C/C(C(CC#CC)C)=O)([H])C/C(C2)=C/CCCC(O)=O

Molecular Formula

C22H30O4

Molecular Weight

358.47

References & Citations

[1]Schrör K, et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK 36 374) --equipotent to PGI2 in vitro. Naunyn Schmiedebergs Arch Pharmacol. 1981 Jun;316 (3) :252-5. |[2]Kowalczyk-Zieba I, et al. Iloprost affects in vitro maturation and developmental competence of bovine oocytes. Theriogenology. 2020 Nov;157:286-296.