5-cis-15 (R) -Iloprost
5-cis-15 (R) -Iloprost (5-cis-15 (R) -Ciloprost) is the C-5 cis-isomer and 15 (R) -epimer of Iloprost. Iloprost is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research[1][2][3][4].
Product Specifications
Product Name Alternative
5-cis-15 (R) -Ciloprost; 5-cis-15 (R) -ZK 36374
UNSPSC
12352211
Target
Drug Isomer; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology
Smiles
O[C@@H]1C[C@@]2([H])[C@]([C@H]1/C=C/[C@@H](C(CC#CC)C)O)([H])C/C(C2)=C\CCCC(O)=O
Molecular Formula
C22H32O4
Molecular Weight
360.49
References & Citations
[1]Kowalczyk-Zieba I, et al. Iloprost affects in vitro maturation and developmental competence of bovine oocytes. Theriogenology. 2020 Nov;157:286-296.|[2]Hildebrand M. Pharmacokinetics of iloprost and cicaprost in mice. Prostaglandins. 1992 Nov;44 (5) :431-42.|[3]Olave N, et al. Iloprost attenuates hyperoxia-mediated impairment of lung development in newborn mice. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315 (4) :L535-L544.|[4]Schneider MR, et al. Effects of prostacyclin analogues in in vivo tumor models. Adv Prostaglandin Thromboxane Leukot Res. 1991;21B:901-8.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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